Structural Organization of Proteins
There are different protein structures, and these correspond directly to the kinds of functions that the proteins address. While many people feel that protein is all the same, this is not the truth. With a number of different kinds of proteins and a wide array of uses for them, it stands to reason that the structural organization of proteins will be different based on each one of those proteins and what type of function it has (Murray, et al., 2006). However, all proteins are similar in that they fold in three dimensions. The structure of the proteins are organized in a hierarchy that begins with the primary structure and moves through to the quaternary structure. Motifs and domains are the higher-level structures (Murray, et al., 2006). The primary structure services the polypeptide chain, and is a sequence of various residues (Van Holde & Matthews, 1996). That is generally where the similarities end, and the wide variety of formations in the structural organization of proteins comes from the number of different sequences that are available in the amino acid residues. Without those differences, all proteins would be much more similar to one another, but that could also restrict them too much and keep them from doing the jobs for which they are currently designed.
All proteins are constructed out of amino acids. A dipeptide is when two amino acids link together. Oligopeptide is the term used for three to nine amino acids linked to one another, and polypeptide...
structure of Jann_2411( DUF14790) from Jannaschia sp at 1.45 A resolution reveals a new fold ( the ABATE domain) and suggests its possible role as transcription regulator" The purpose of this study was to resolve the structure of the protein Jann_2411 and relate its structure to the functional properties of the protein. The researchers determined the structure using the method of x-ray crystallography (multiple wavelength anomalous diffraction) and structural analysis
Tumor Suppressor p53 The p53 tumor suppressor, also known as the TP 53 or tumor protein can be referred to as a gene that codes for a protein that is responsible for the regulation of the cycle of the cell and therefore acting as tumor suppression. It is significant for cells in multicellular organisms to suppress cancer, p53 has been referred to as ‘the guardian of the genome’ as extracted from
Enzymes 1. How does temperature affect enzyme function? Every enzyme demonstrates maximum activity at a particular temperature known as its optimum temperature. Generally, all enzymes are inactivated at temperatures below 10°C and get denatured (lose its three-dimensional protein nature) above its optimum temperature (Seager & Slabaugh 2010). Experiments conclude that enzyme activity increases by almost ten percent coupled to each degree rise in temperature until it reaches its optimum state and declines beyond
DNA The Structure and Nature of DNA DNA, or deoxyribonucleic acid, is the basic system upon which life on Earth is constructed. In a very real sense, DNA is a kind of program for life that cells use to replicate themselves and transmit information from generation to generation. Over eons, as life changes and adapts to new environmental conditions, that information is stored in the genetic code of all life on the
growing demand for functionally superior protein gives us an excellent opportunity for endeavoring to improve the foaming properties of whey protein isolates (WPI) is dairy companies. There are several factors that effect the foaming properties of whey protein isolate. These include the following: internal elements amino acid composition and sequence other structures inherent to the WPI hydrophobic / hydrophilic character of the WPI surface the overall charge and the distribution of
Soy Protein and Bone Health in Women Soy, a protein-rich legume, has been prominently featured in the traditional cuisines of Far Eastern cultures for thousands of years. In addition to its high protein content, soy also contains the other two macronutrients, carbohydrates and fats, as well as many vitamins, minerals and other micronutrients such as calcium, folic acid, and iron. Dietary sources of soy protein include soybeans, tofu, beans curd, tempeh,
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